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Prostate Specific Antigen (PSA) (Middle Region) Peptide

PSA 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN979078
发货至: 中国

Quick Overview for Prostate Specific Antigen (PSA) (Middle Region) Peptide (ABIN979078)

抗原

Prostate Specific Antigen (PSA)

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    LRPGDDSSHD LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI

    产品特性

    This is a synthetic peptide designed for use in combination with anti-KLK3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    Prostate Specific Antigen (PSA)

    背景

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

    Alias Symbols: APS, KLK2A1, PSA, hK3

    Protein Interaction Partner: AR,POLR2A,CTNNB1,KAT5,RUVBL1,A2M,ALB,EPOR,FN1,IGFBP3,PLG,PTHLH,PZP,SEMG1,SEMG2,SERPINA1,SERPINA3,SERPINA5,SLPI,A2M,SERPINA1,SERPINA5

    Protein Size: 261

    分子量

    26 kDa

    基因ID

    354

    NCBI登录号

    NM_001648, NP_001639

    UniProt

    P07288
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